A54-year-oldwomanwithprogressiveweaknessofrightlimb

Whatisyourdiagnosis?

TheanswerisBalósConcentricSclerosis

Balósconcentricsclerosisisarareformofmultiplesclerosisvariantcharacterizedbypathologicfindingsofalternatingringsofmyelinpreservationorremyelinationandmyelinloss.

TypicalimagingfindingsarealternatingbandsofdemyelinatedandmyelinatedwhitematterseenonT2-weightedMRimages.

TheconcentricpatternscanbebetterrevealedbydiffusionweightedimagethanT2WIbyshowingrestrictedwaterdiffusioninactivedemyelinatingbands.

中文版：

女性，54岁，进行性右侧肢体无力

诊断：Balos同心圆硬化

Balos同心圆硬化为多发性硬化的少见形式，其病理特征为正常的髓鞘或髓鞘再生与髓鞘脱失呈环形交替排列。

MRIT2WI典型表现为脱髓鞘脑白质与正常脑白质呈带状交替排列。

活动性的脱髓鞘区域在弥散加权成像呈高信号，因此，DWI较T2WI显示更佳。

FromAJNRClassicCase